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Han WT mice both at baseline (-23.3 ) and after 4 hr of infection (-89.53 ), but by the 24 hour time point its levels weremarkedly higher in the SP-A-/- mice (93.8 ), indicating a delayed response in the SP-A-/- mice. c) Potential pathways affected by changes We also used the Ingenuity Systems Pathways Analysis program to better understand the functional implications of the absence of SP-A, both
Han WT mice both at baseline (-23.3 ) and after 4 hr of infection (-89.53 ), but by the 24 hour time point its levels weremarkedly higher in the SP-A-/- mice (93.8 ), indicating a delayed response in the SP-A-/- mice. c) Potential pathways affected by changes We also used the Ingenuity Systems Pathways Analysis program to better understand the functional implications of the absence of SP-A, both
Change for both proteins was greater in the SP-A-/- mice than in WT. It should be pointed out that we did not observe corresponding increases in other serum proteins including albumin, ceruloplasmin, and haptoglobin indicating that these increases in hemoglobin are probably not due to serum protein leakage into the alveolar spaces. Hemoglobin expression has been shown to occur in alveolar epithel


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