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Nd norepinephrine were elevated above the control level. Data in table 5 reveal that Na+, K+-ATPase activity and total protein content in the two groups exposed to gasoline were lower than the control, although no significant difference was found between each other. The rats exposed to the unleaded gasoline had a significantly lower acetylcholinesterase activity as compared with the control or le
Ecules or to relative reduction in acetylcholinesterase-containing neurons, thus potentiating cholinergic effects. In the present study, no statistical differences were detected among the serotonin levels of the cerebral cortex in the three groups; the control, the leaded and the unleaded. However, in the hypothalamus, hippocampus, cerebellum, the serotonin level was lower in the groups exposed t
Elated compound, causes neurodegeneration, whereas peripheral treatment causes DM. Hypothesis: Limited early exposures to nitrosamines that are widely present in the environment, enhance the deleterious effects of high fat intake in promoting T2DM and neurodegeneration. Methods: Long Evans rat pups were treated with N-nitrosodiethylamine (NDEA) by i.p. injection, and upon weaning, they were fed w
Between the groups inhaled the leaded gasoline and the control. The GSH content was lower in both the leaded and unleaded gasoline groups than the control group, but GSH in the unleaded group was higher than in the leaded group. The unleaded gasoline exposed group exhibited a significant decrease in superoxide dismutase activity in comparison with either the leaded gasoline or the control groups.
N male rats.Parameter Duration of aggression/sec GROUP Control Leaded gasoline Unleaded gasoline Tooth chattering 0.9 ?0.23 4.7 ?1.1 a** 4.4 ?0.92 a* Threat posture 1.5 ?0.54 6 ?1.2 a* 6.2 ?1.31 a* Leaping and biting 1.9 ?0.72 5.5 ?1.45 5.9 ?1.50 Boxing position 1 ?0.42 2.2 ?0.63 2.2 ?0.Values are expressed as means ?SE a: significantly different from the control group. Asterisks indicate the lev
Terbalance the tendency of two other major neurotransmitters in the brain dopamine and noradrenaline to encourage overarousal, fear, anger, tension, aggression, violence, obsessive-compulsive actions, overeating, anxiety and sleep disturbances [60].Page 8 of(page number not for citation purposes)BMC Physiology 2009, 9:http://www.biomedcentral.com/1472-6793/9/ConclusionThe present results revealed
Terbalance the tendency of two other major neurotransmitters in the brain dopamine and noradrenaline to encourage overarousal, fear, anger, tension, aggression, violence, obsessive-compulsive actions, overeating, anxiety and sleep disturbances [60].Page 8 of(page number not for citation purposes)BMC Physiology 2009, 9:http://www.biomedcentral.com/1472-6793/9/ConclusionThe present results revealed
N male rats.Parameter Duration of aggression/sec GROUP Control Leaded gasoline Unleaded gasoline Tooth chattering 0.9 ?0.23 4.7 ?1.1 a** 4.4 ?0.92 a* Threat posture 1.5 ?0.54 6 ?1.2 a* 6.2 ?1.31 a* Leaping and biting 1.9 ?0.72 5.5 ?1.45 5.9 ?1.50 Boxing position 1 ?0.42 2.2 ?0.63 2.2 ?0.Values are expressed as means ?SE a: significantly different from the control group. Asterisks indicate the lev
Terbalance the tendency of two other major neurotransmitters in the brain dopamine and noradrenaline to encourage overarousal, fear, anger, tension, aggression, violence, obsessive-compulsive actions, overeating, anxiety and sleep disturbances [60].Page 8 of(page number not for citation purposes)BMC Physiology 2009, 9:http://www.biomedcentral.com/1472-6793/9/ConclusionThe present results revealed
Ither the leaded or unleaded group as compared with the control. On the contrary, dopamine was elevated in the cerebellum of leaded exposed group above both the unleaded gasoline and control. The fluctuations in the levels of dopamine in different brain areas may be related to the effects MMT which is an organic manganese (Mn) compound added to unleaded gasoline and the mechanisms of Mn neurotoxi
Anied with a higher tendency towards aggressive behaviour as a consequence to gasoline inhalation.11. 12.13. 14.AbbreviationsNa+, K+-ATPase: total adenosine triphosphatase; SOD: superoxide dismutase; AChE: acetylcholinesterase; GSH: reduced glutathione; TBARS: lipid peroxidation; DA: dopamine; NE: norepinephrine; 5-HT: serotonin; CNS: central nervous system; ROS: reactive oxygen species; MMT: met
Ecules or to relative reduction in acetylcholinesterase-containing neurons, thus potentiating cholinergic effects. In the present study, no statistical differences were detected among the serotonin levels of the cerebral cortex in the three groups; the control, the leaded and the unleaded. However, in the hypothalamus, hippocampus, cerebellum, the serotonin level was lower in the groups exposed t
Ither the leaded or unleaded group as compared with the control. On the contrary, dopamine was elevated in the cerebellum of leaded exposed group above both the unleaded gasoline and control. The fluctuations in the levels of dopamine in different brain areas may be related to the effects MMT which is an organic manganese (Mn) compound added to unleaded gasoline and the mechanisms of Mn neurotoxi
D the colour was developed upon the addition of DTNB - Phosphate - ethanol reagent. The colour was then read immediately at 412 nm and the enzyme activity was determined in M per SH group (MSH) from a standard curve.Determination of total proteins The total protein content was determined according to the method described by Lowry et al. [32]. This method is based on the reaction between the trypt


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