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A, impaired autoregulation, neurogenic shock, radial and axial hemorrhage, compromised microcirculation, collapsed veins, venous obstruction, vasospasm and thrombosis. 3. Ionic alterations: intracellular and extracellular calcium overload, increase of sodium and potassium. 4. Accumulation of neurotransmitters such as dopamine, norepinephrine, serotonin and glutamate at the extracellular level. 5.

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